1.
Blood volume
a.
Can be measured
by a dilution technique using inulin
b.
Is approximately
7% of the body weight of an adult
c.
Relative to the
body weight in an infant is less than in an adult
d.
Is decreased by
long residence at high altitude
e.
Is increased in
pregnancy
2.
With knowledge of
the packed cell volume following can be used to measure the blood volume
a.
Chromium labelled
red blood cells
b.
Inulin
c.
Sodium
thiocyanate
d.
Evans blue
e.
Iodinated human
serum albumin
3.
Cytotoxic killer
cells
a.
Kill by releasing
perforins into the target cells
b.
Formation is
stimulated by helper T cells
c.
Do not play a
role in the development of autoimmunity
d.
Are increased in
transplant recipients
e.
Stimulate humoral
immunity
4.
Eosinophilia
occurs in
a.
Asthma
b.
Acute bacterial
infection
c.
Helminthic
infestation
d.
Military TB
e.
Hepatic cirrhosis
5.
Increased
eosinophils are found in
a.
TB
b.
Syphilis
c.
Acute adenitis
d.
Hodgkin’s disease
e.
Lymphosarcoma
6.
Plasma cells
a.
Are strongly
phagocytic
b.
Are normally
present in bone marrow
c.
Contains large
amount of RNA
d.
Synthesizes
proteins
e.
Produces
immunoglobulins
7.
Lymphocytes
a.
Are found only in
the lymph nodes
b.
Have a shorter
life than neutrophils
c.
Can be
transformed into blast cells
d.
Stimulated to
multiply by corticosteroids
e.
Are particularly
sensitive to radiation
8.
T lymphocytes
a.
Do not
participate in humoral immunity
b.
Are responsible
for the production of lymphokines
c.
Are transformed
into plasma cells
d.
Are activated by
interleukins
e.
Are significantly
depleted in the AIDS complex
9.
Red blood cells
a.
Haemolyse in
hypertonic saline
b.
Disintegrate to
release erythropoietin
c.
Are relatively
inelastic
d.
Are smaller than
normal in foliate deficiency
e.
Are smaller than
normal in iron deficiency
10.Haemoglobin
a.
Contains ferric
irons
b.
May be oxidized
to methaemoglobin
c.
Combines with
carbon dioxide
d.
Is a stronger
acid when oxygenated
e.
Has the same
molecular structure as myoglobin
11.Haemoglobin
a.
Has a greater
affinity for carbon monoxide than for oxygen
b.
Is not filtered
at the renal glomeruli
c.
Has the same
molecular weight as myoglobin
d.
Is formed in the healthy
adult at a rate of about 6g/day
e.
Concentration in
red cells rises in macrocytic anaemia
12.
Fetal haemoglobin
a.
Has one iron atom
per molecule
b.
Has a different
amino acid composition in globin as compared with adult haemoglobin
c.
Has an O2
dissociation curve shifted to the right as compared to adult haemoglobin
d.
Is present in the
blood in sickle cell disease
e.
Oxygen uptake is
not affected by chances in the pCO2
13.Diagnostic
features of homozygous thalassaemia include
a.
Hypochromia
b.
Reduction in HbA2
c.
Increase in HbF
d.
Normal or high
serum iron
e.
Megaloblasts in
the bone marrow
14.Following
are frequently seen in sickle cell disease in the adult
a.
Splenomegaly
b.
Jaundice
c.
Dysphagia
d.
Aseptic necrosis
of bone
e.
Leg ulcers
15.The
age of 70 years red cell formation is found in the bone marrow of
a.
Femur
b.
Tibia
c.
Vertebrae
d.
Sternum
e.
Ribs
16.Erythropoiesis
a.
In the fetus
takes place in liver and spleen
b.
Is stimulated by
hypoxia
c.
Is increased in
hypothyroidism
d.
Is decreased in
myeloid leukaemia
e.
Stimulated by
aldosterone
17.Erythropoietin
a.
Cases a rise in
the reticulocyte percentage
b.
Level in blood is
reduced after bilateral nephrectomy
c.
Is essential for
the synthesis of haemoglobin
d.
Is a glycoprotein
e.
Is secreted by
cells in the bone marrow
18.Erythropoietin
a.
Is secreted by
cells of the liver
b.
Secretion is
increased in cyanotic congenital heart disease
c.
Level in plasma
is increased during residence in high altitude
d.
Increases the
number of red cell precursors in bone marrow
e.
Has an immediate
action in increasing the circulating red cells
19.Red
cell breakdown products increase
a.
Plasma bilirubin
b.
Porphyrins in the
urine
c.
Haemosiderin
depositon
d.
Plasma alkaline
phosphate
e.
Blood uric acid
concentration
20.Bilirubin
a.
Is mainly
produced in the liver
b.
In the
unconjugated state is moderately soluble in water
c.
Is conjugated
with glucoronic acid in the liver
d.
Is converted to
urobillinogen in the liver
e.
Is found in the
urine in haemolytic anaemia
Answers Soon..
