Gardener syndrome This comprises multiple osteomas (particularly of the jaws and facial bones),multiple polyps of the large intestine, epidermoid cysts, and fibromas of the skin. It shows autosomal dominant inheritance. The discovery on clinical or X-ray examination of facial osteomas mandates examination of the lower gastrointestinal tract, as these polyps have a tendency to rapid malignant change. This is a highly 'worthwhile' syndrome.
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