Romberg syndrome (hemifacial atrophy) consists of progressive atrophy of the soft tissues of half the face, associated with contralateral Jacksonian epilepsy and trigeminal neuralgia. Rarely, half the body may be affected. It starts in the first decade and lasts ~3 yrs before it becomes quiescent.
|Romberg syndrome (hemifacial atrophy)|
Papillon-Lefevre syndrome is palmoplantar hyperkeratosis and juvenile periodontitis, which affects both primary and secondary dentition. Normal dental development occurs until the appearance of the hyperkeratosis of the palms and soles, then simultaneously an aggressive gingivitis and periodontitis begin. The mechanism is not well understood.