Acute inflammation - General Pathology Multiple Choice Questions (MCQ) - With Answers

       

    True and False type MCQ's

     01.Acute inflammation
a.     Heal by suppuration with abscess formation
b.     Completely heal by resolution
c.      Heal with fibrosis
d.     Heal with regeneration
e.     Leads to amyloidosis
        
02  Regarding acute inflammation
a. Active hyperaemia is due to increased venous pressure
b. Increased pressure is due to gaps in basement membrane
c. Prostaglandin is an endogenous mediator of increased venous pressure
d. Excess proteins are removed by lymph
e. Cellular inflammatory exudates has low O2 tension

03. Regarding acute inflammation
a. Active hyperaemia is due to arteriolar relaxation
b. Angiotensin is an endogenous mediator causing increase in permeability
c. Monocyte infiltration is an active process
d. Increased permeability is due to gaps in the basement membrane
e. Proteins are taken into the lymphatics by pinocytosis

04. Regarding acute inflammation
a. It does not depend on the structure of the tissue affected
b. Mild acute inflammation is healed by the granulation tissue formation
c. In mild acute inflammation the cardinal signs of inflammation cannot be seen
d. Dilation of blood vessels are due to stimulation of autonomic innervation of arterioles
e. In severe inflammation cell necrosis may occur

05. Regarding acute inflammation
a. Migration of monocytes is a passive process
b. Fibrin network forms a mechanical barrier to the spread of bacteria
c. Promotion of immunity is due to antibody mediated immunity as well as cell mediated immunity
d. Slowing of blood flow preceded by active hyperaemia
e. Formation of granulation tissue leading to fibrosis is a recognized sequale

06. “Triple response” of acute inflammation is characterized by
a. Redness of the injury followed by reflex vasodilation
b. Local tissue wheal representing swelling
c. Development of heat
d. Involvement of both a local nerve reflex and a histamine response
e. Increased reaction due to a mixture of polypetides

07. Effects of acute inflammation include
a. Prevention of local tissue injury by dilution of the toxin
b. Prevention of spread of organism by forming a fibrin network
c. Maintaining long term immunity by promoting antibody formation
d. Destruction of microorganisms due to heat
e. Healing of the injury by promoting immobility due to pain

08. Cells that take part in acute inflammation include
a. Plasma cells
b. Mast cells
c. Lymphocytes
d. Polymorphonuclear leucocytes
e. Macrophages

09. Exudate occurs as a result of
a. Increased capillary permeability
b. Direct action of prostacycline and complement
c. Chemical mediators
d. Axonal reflex via substance P
e. Prostaglandin action

10. In acute inflammation oedema is produced by
a. increased capillary permeability
b. Direct reflex
c. Neural reflex
d. Antibody reactions
e. Increased intravascular pressure

11. Substances important in the increased vascular permeability of acute inflammation include
a. Globulin permeability factor
b. Cortisol
c. Histamine
d. Plasma kinines
e. Seratonin

12. Essential features of abscess formation are
a. Eosinophil leucocytosis
b. Destruction of tissue
c. Pyaemia
d. Septicaemia
e. Neutrophil leucocytosis

13. Regarding chronic inflammation
a. Important feature is production of vascular granulation tissue
b. Nature of the lesion depend on the intensity and persistence of the stimulation
c. Most of the migrating cells into the injured tissue are mononuclear cells
d. It gives rise to serious effects by narrowing orifices and tubes
e. Fibrosis tissue formation always have harmful effects

14. Regarding chronic inflammation
a. Microorganisms ingested by macrophages are destroyed by it
b. In autoimmune thyroiditis it serves a useful function
c. In arteritis, fibrous tissue formation strengthens the arterial wall
d. Presence of large numbers of lymphocytes suggest hypersensitivity
e. Production of vascular granulation tissue is important feature

15. Malignant disease may complicate the chronic inflammatory conditions
a. Sarcoidosis
b. Ulcerative colitis
c. Chronic osteomyelitis
d. Asbestosis
e. Schistosomiasis

16. Granulomas are characteristically found in
a. Beryllium pneumonitis
b. Leprosy
c. Tuberculosis
d. Syphilis
e. Coccidiodomycosis

17. Granuloma is a type of inflammatory reaction characteristic of
a. Tuberculosis
b. Rheumatoid arthritis
c. Regional ileitis
d. Staphylococcal pyaemia
e. Sarcoidosis

18. Cells which may be found in granulomas
a. Plasma cells
b. Giant cells
c. Lymphocytes
d. Epithelioid cells
e. Macrophages

19. Epithelial cell granulomas are seen in
a. Typhoid fever
b. Crohn’s disease
c. Foerign body reactions
d. Tuberculosis
e. Alcoholic hepatitis

20. Caseous granuloma are seen in
a. Tuberculosis
b. Lupus vulgaris
c. Sarcoidosis
d. Foreign body granulomas
e. Inflammatory bowel disease

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