Pleomorphic adenoma

Pleomorphic adenoma

· Account for about 75% of parotid tumors

· Arise mainly from duct epithelum or myoepithelial cells

Important histological features

· Capsule never complete

· Ducts

· Sheets or stands of dark staining epithelial cells

· Squamous metaplasia and focci of keratin

· Fibrous and elastic tissue

· Myxoid tissue

· Cartilage,sometimes calcified,rarelytrue bone formation.

· The fibroid,myxoid,or cartilagenous,mesenchymal elements are due to the pluripotential properties of myoepithilial cells.

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